LMH growing

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Chicken Liver Hepatocellular carcinoma cell line LMH

Organism: Gallus gallus (chicken)
Strain: Leghorn
Tissue: Liver
Morphology: Epithelial; Dendritic like.
Celltype: hepatocellular carcinoma; induced using diethylnitrosamine.
Growth Properties: adherent
Description: The cell line LMH was established in 1981 by Tomoyuki Kitagawa (see reference below) at the Cancer Institute, Kami-Ikebukuro-ku of Tokyo, Japan. Primary hepatocellular carcinoma epithelial cell lines were transformed into permanent cells by inducing tumorous nodules by long term treatment with diethylnitrosamine in the liver of a male leghorn cchicken. LMH cells are inducible for the expression of the liver specific apolipoprotein II (apoll) gene.